Pharma supply chains are getting more complex, and recent disruptions show how fragile they can also be. On top of that, the lack of transparency increasingly causes human rights violations and contributes to climate change. This has an effect on the legislative landscape that aims at tackling these issues. In response, Responsible Procurement is a term rapidly spreading into the corporate floors, tackling the sustainability agenda from operational side rather than the high level strategic. Responsible procurement seeks to embed environmental, social, and ethical risks into standard procurement procedures and processes for engaging with vendors. With the growing shift towards ESG and incoming supply chain legislation across the world, the practice of responsible sourcing is gaining ground and a key focus for the pharmaceutical industry.

Recognizing that upstream Scope 3 greenhouse gas (GHG) emissions constitute a major share of a chemical or pharmaceutical company’s emissions, increasing emission data transparency and accuracy is crucial to drive emission reductions along the value chain.

In September 2022, Together for Sustainability (TfS) launched the Product Carbon Footprint (PCF) Guideline. It enables companies to calculate the PCFs of their chemical materials more precisely in a way that is harmonized across the industry, while remaining fully compliant with less specific international standards for GHG accounting. The PCF Guideline is open source.

This short session answers the most pressuring strategic questions with regards to sustainability: Why does it matter? Where to focus? How is it measured? What is the current industry status? How to improve?

Indena is relentlessly working to generate a sustainable impact on its stakeholders, cultivating with care its own precious circle: Nature, Technology, and People. In terms of actual projects and actions, Indena's commitment in sustainability includes responsible supply chain management, a circular economy in product design, and very smart use of energy in its plants. As for energy use, which is linked to climate change, one of the most urgent global sustainability challenges, Indena has been working for years to reduce consumption, save energy, and achieve high levels of energy self-production. All the actions taken for sustainability allow Indena to be fully reliable in terms of business continuity and thus be a solid partner for all its clients.

Container closure integrity (CCI) testing is determined by evaluating whether a given container maintains its sterile barrier. It is a mandatory step in the design verification phase of a drug – device combination product development. Several methods exist with different advantages and limitations. During this session, we will address the following points:

- Probabilistic vs deterministic CCI Testing

- Presentation of the different deterministic CCI testing methods with applications and limitations

- What to consider when selecting CCI testing method.

At the end of the session, attendees should better understand the influence of the drug specificities to select the most suitable technical option for Container Closure Integrity testing activities based on the advantages and limitations of different techniques available on the market.